How Donations Work

When you join Pareto you take the first step towards being the cure for patients suffering from leukemia, lymphoma, and anemia. 


HLA Testing

To join Pareto a simple HLA test is all it takes!. Pareto tests a sample of cells collected through an easy to use cheek swab kit. In the comfort of their home, donors can swab the inside of their cheek with a q-tip kit and then Pareto takes care of the rest. This sample is then compared with specific protein markers, known as human leukocyte antigens (HLA,) with HLA markers of patients who need to be matched for a stem cell transplant.

Matching Process

Matching begins when a Doctor initiates a search on Pareto's database to find donors with HLA types that match their patients. These searches happen on behalf of patients every day, so the most important thing you can do as a member is stay committed.

When a Pareto member matches a patient, there are several simple confirmatory steps before donating. These steps are meant to ensure donation is safe for both the donor and the patient.

Donation Process

Once approved to donate, the patient’s doctor will request peripheral blood stem cells (PBSC). 

HLA Testing

How donated cells help patients

A healthy blood system is always making new blood-forming cells. These are necessary for survival. If the body begins making diseased cells or not enough healthy cells, a stem cell transplant may be the best treatment and only potential cure.

During transplant, the donor’s healthy blood-forming cells are put into the patient’s bloodstream. These donated cells move through the patient’s bloodstream and settle in the bones. This is where the donated cells will produce new blood-forming cells. 

Each patient needs a donor who is a close HLA match. This is different than blood type. Since HLA is part of your unique DNA, every person who joins Pareto gives a patient the hope for a cure. You may never be identified as a match for someone, or you might be one of a number of potential matches. But you may also be the only member who can save a patient’s life. The most important thing you can do is stay committed and respond if contacted!